And the pesticide metabolites, which are often times more detrimental to mammals, like in products such as Fipronil, find its way to humans not only on our food but also in our food with staples such as rice (that the seed itself is pretreated), but also in the water supply as it leaches from the soil. The effects of long-term exposure, even in small quantities, can damage mitochondrial function, significantly affecting energy production, the lack of which can trigger a number of different disease processes.